Watermelon Serves Up Medially Important Amino Acid       Lycopene Leader
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Watermelon Serves Up Medically Important Amino Acid
By Erin Peabody, USDA

Nothing says you care like the gift of a small watermelon. At least that's the custom in China, where the offer of this red-fleshed cucurbit is considered a fine way to please a gracious host or ill friend.

Now scientists with the Agricultural Research Service (ARS) have found that there's far more to this gastronomic gesture than just tradition and good taste. In addition to containing plentiful amounts of the health-promoting antioxidant lycopene, watermelon is an excellent source of the amino acid citrulline.

And ARS researchers in Lane, Oklahoma, and their collaborators have found that not only are watermelon's citrulline stores abundant--they're also readily usable. Their findings are reported in the current issue of the journal Nutrition. The human body uses citrulline to make another important amino acid—arginine—which plays a key role in cell division, wound healing and the removal of ammonia from the body.

ARS plant physiologist Penelope Perkins-Veazie and nutritionist Julie Collins were interested in finding out just how bioavailable watermelon's citrulline is, since the fruit is one of few foods to contain high levels of it. Perkins-Veazie works at the ARS South Central Agricultural Research Laboratory in Lane, while Collins—previously based at the Lane laboratory—works at Eastern Oklahoma State College in Wilburton. The two collaborated with amino acid expert Guoyao Wu at Texas A&M University in College Station.

After analyzing the arginine levels of volunteers who'd recently consumed differing amounts of concentrated watermelon juice, the scientists determined that ingesting the juice increased the volunteers' levels of plasma arginine—likely from conversion of citrulline.

Medical researchers are currently evaluating arginine as a possible treatment for high blood pressure, elevated glucose levels and the vascular complications associated with sickle-cell disease. If such studies pan out, concentrated forms of watermelon could represent an all-natural amino acid source. The fruit's good-for-the-body lycopene is an added bonus.  Perkins-Veazie is now focused on finding an optimal way of extracting citrulline from watermelon.

ARS is the U.S. Department of Agriculture's chief scientific research agency.  http://www.ars.usda.gov/is/pr/2007/070321.htm

                

Lycopene Leader

Watermelon is the Lycopene Leader in fresh produce, having higher concentrations of lycopene than any other fresh fruit or vegetable. In fact, fresh watermelon contains higher levels of lycopene than fresh tomatoes - a 2-cup serving of watermelon contains and average of 18.16 mg and one medium-sized tomato contains 4 mg.

Heart Healthy

Watermelon has heart healthy properties because it is naturally low in saturated fat, total fat and cholesterol.

A recent study by the United States Department of Agriculture (USDA) about watermelon consumption and heart healthy benefits was completed and published March 2007. The NWPB has four new structure-function claims derived from this study:

1. Watermelon consumption increases free arginine and citrulline, which can help maintain cardiovascular function.

2. Eating watermelon can help maintain cardiovascular health.

3. Watermelon has amino acids such as citrulline and arginine that help maintain the arteries.

4. Watermelon amino acids citrulline and arginine can help maintain blood flow and heart health.

Vitamins & Minerals

Watermelon Is Practically A Multivitamin Unto Itself
A 2-cup serving of watermelon is an excellent source of Vitamins A, B6 and C.

Vitamin A found in watermelon is important for optimal eye health.

Vitamin B6 found in watermelon is used by the body to manufacture brain chemicals (neurotransmitters), such as serotonin, melatonin and dopamine, which preliminary research shows may help the body cope with anxiety and panic.

Vitamin C in watermelons can help to bolster your immune system's defenses against infections and viruses and is known to stimulate the immune system and protect against free radical damage.

Potassium
A two-cup serving of watermelon is also a source of potassium*, a mineral necessary for water balance and found inside of every cell. People with low potassium levels can experience muscle cramps. A two-cup serving has less than 10 percent of the daily reference value for potassium.